PIPERINE-LOADED CHITOSAN NANOPARTICLES: PREPARATION AND CHARACTERIZATION
نویسندگان
چکیده
Abstract – HCTN7. Plasma cholesterol level plays an important role in atherosclerosis and cardiovascular diseases. Piperine, alkaloid form of black pepper is known to reduce uptake. In this paper, piperine-loaded chitosan nanoparticles (CTS-PIP NPs) were prepared by ionic gelation method. Molecular interactions among the components confirmed FT-IR spectroscopy. Transmission electron microscopy (TEM) images revealed spherical-shaped with diameter <100 nm. CTS-PIP NPs displayed positive ζ-potential(ZP) about 31.6 mV. Dynamic light scattering (DLS) particle size (PS) distribution analysis indicated mean was 245.9 nm, polydispersity index 31%
منابع مشابه
Preparation and Characterization of Rivastigmine Loaded Chitosan Nanoparticles
Nanotechnology mediated drug delivery has been reported to enhance the drug efficacy, bioavailability, reduce toxicity and improve patient compliance by targeting the cells and tissues to produce desired pharmacological action. Aim: The purpose of the present study was to formulate and evaluate rivastigmine loaded chitosan nanoparticles for sustained release. Methods: Rivastigmine is a short ac...
متن کاملPreparation and Evaluation of Vancomycin-Loaded N-trimethyl Chitosan Nanoparticles
Chronic intracellular infections caused by drug-resistant pathogens pose a challenge to the treatment of chronic osteomyelitis. Such treatment requires an intracellular delivery system for the sustained release of antibiotics such as vancomycin (VCM), which is an antibiotic of last resort used against many clinically resistant bacteria. In this work, we report VCM-loaded N-trimethyl chitosan (T...
متن کاملPreparation and Characterisation of Highly Loaded Fluorescent Chitosan Nanoparticles
Chitosan (CS) nanoparticles have been developed as a versatile drug delivery system to transport drugs, genes, proteins, and peptides into target sites. Demands on fluorescent nanoparticles have increased recently due to various applications in medical and stem-cell-based researches. In this study, fluorescent CS nanoparticles were prepared by a mild method, namely, complex coacervation. Entrap...
متن کاملPreparation and antioxidant properties of selenium nanoparticles-loaded chitosan microspheres
Selenium nanoparticles (SeNPs), as a special form of selenium (Se) supplement, have attracted worldwide attention due to their favorable properties and unique bioactivities. Herein, an eco-friendly and economic way to prepare stable SeNPs is introduced. SeNPs were synthesized in aqueous chitosan (CTS) and then embedded into CTS microspheres by spray-drying, forming selenium nanoparticles-loaded...
متن کاملPreparation and characterization of Tribulus terrestris-loaded nanoparticles
Background and objectives: Tribulus terrestris is a flowering herb (Zygophyllaceae) with several properties in folk medicine such as diuretic, tonic, aphrodisiac, analgesic, astringent, and stomachic-lithotripter activities. Although, some extracts and phytochemicals represent excellent bio-activity in vitro, less or no in vivo activity is observed du...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Vietnam Journal of Science and Technology
سال: 2021
ISSN: ['2525-2518']
DOI: https://doi.org/10.15625/2525-2518/59/4/15523